Kuželove semináre / Kužela Lectures

Organized by the Departments of Biochemistry and Genetics, Faculty of Natural Sciences,

Comenius University in Bratislava in close collaboration with Natura, o.z.


Upcoming lectures:

112. Lecture [2019]


Anna Ohradanova-Repic - Medical University of Vienna, Austria 

Abstract [PDF]

Previous lectures:


111. Lecture [13/11/2018]

Evolution of flower colour in snapdragons

Nick Barton - Institute of Science and Technology (IST Austria), Klosterneuburg, Austria 

Abstract [PDF]

110. Lecture [11/05/2018]

Science behind laboratory testing: To test or not to test?

Maja Chloupková - Legacy Laboratory Services, Portland, USA. 

Abstract [PDF]


109. Lecture [24/11/2017]

The dynamics of nucleoprotein filaments formed by human RAD51 - DNA recombinase

Mário Špírek - Department of Biology, Masaryk University & International Clinical Research Center, St. Anne's University Hospital Brno, Czech Republic. 

Abstract [PDF]

108. Lecture [10/11/2017]

Why is our immune system selfish?

Tomáš Doležal - University of South Bohemia, České Budějovice, Czech Republic. 

Abstract [PDF]

107. Lecture [06/06/2017]

Translational bypassing and other forms of recoding

John F. Atkins - University College Cork (Ireland), University of Utah (USA)

Abstract [PDF]

106. Lecture [31/03/2017]

The first 30 years of T-cell receptor signaling: still searching for a trigger

Dominik Filipp - Ústav molekulární genetiky, AV ČR, Praha, Česká republika. 

Abstract [PDF]


105. Lecture [23/11/2016]

ABP Gene Copy Number Variation (CNV) in Wild Mus musculus populations

Christina M. Laukaitis & Robert C. Karn

Departments of Medicine and Nutrition, University of Arizona College of Medicine, Tuscon, AZ, USA

Abstract [PDF]

104. Lecture [18/5/2016]

Found in translation: From genomics to novel gene functions

Andrea Pauli - The Research Institute of Molecular Pathology, Vienna, Austria

Abstract [PDF]

103. Lecture [4/3/2016]

Monoxenous trypanosomatids are model organisms to study origin of parasitism and endosymbiosis

Vyacheslav Yurchenko - Life Science Research Centre, University of Ostrava, Ostrava, Czech Republic

Abstract [PDF]


102. Lecture [05/27/2015]

Protecting the genome by homologous recombination

Maria Jasin - Memorial Sloan Kettering Cancer Center, New York, USA.

Abstract [PDF]

101. Lecture [03/25/2015]

Genome (in)stability: Mechanisms and relevance for cancer development and treatment

Jiří Bártek - Danish Cancer Society Research Center, Copenhagen, Denmark.

Abstract [PDF]

100. Lecture [03/13/2015]

From little science to Big Science

Gottfried Schatz - University of Basel, Switzerland.

Abstract [PDF] [PhotoGallery]

99. Lecture [02/26/2015]

Plant chromosome genomics

Jan Šafář - Institute of Experimental Botany, Olomouc, Czech Republic.

Abstract [PDF]


98. Lecture [05/12/2014]

Homologous recombination: Regulation and therapeutic targeting

Lumír Krejčí - Department of Biology and National Centre for Biomolecular Research, Masaryk University & International Clinical Research Center St. Anne’s University Hospital, Brno, Czech Republic.

Abstract [PDF]

97. Lecture [24/09/2014]

Precision medicine through integrative computational biology

Igor Jurisica - Princess Margaret Cancer Centre, Toronto, Canada.

Abstract [PDF]

96. Lecture [21/03/2014]

To the cell membrane and back again: The role of protein trafficking in adaptive and innate immunity

Vladimír Leksa - Institute of Molecular Biology; Slovak Academy of Science; Bratislava & Medical University of Vienna; Vienna; Austria.

Abstract [PDF]

95. Lecture [14/03/2014]

From Bones to Genomes: Current State of Ancient DNA Research

Stefan Prost - University of Otago, New Zealand & Swedish Natural History Museum, Stockholm, Sweden.

Abstract [PDF]


94. Lecture [15/11/2013]

Recruitment of transcription and processing factors by RNA Polymerase II

Richard Stefl - CEITEC-Central European Institute of Technology, Masarykova Universita, Brno, Česká republika.

Abstract [PDF]

93. Lecture [8/11/2013]

Surveillance of spliceosomal snRNP assembly

David Staněk - Ústav molekulární genetiky, AV ČR, Praha, Česká republika.

Abstract [PDF]

92. Lecture [18/10/2013]

Peroxisome biogenesis

Andreas Hartig - Max F. Perutz Laboratories, Vienna University, Vienna, Austria.

Abstract [PDF]

91. Lecture [15/5/2013]

Immunoreceptor signaling and membrane rafts

Václav Hořejší - Ústav molekulární genetiky, AV ČR, Praha, Česká republika.

Abstract [PDF]

90. Lecture [29/4/2013]

Signalling within the organism

Amotz Zahavi - Department of Zoology, Tel Aviv University, Israel.

Invitation [PDF]


89. Lecture [21/11/2012]

Spontánna regresia nádorov

Ján Lakota - Oddelenie klinickej hematológie a transfuziológie, Národný onkologický ústav, Bratislava.

Abstract [PDF]

88. Lecture [31/10/2012]

Metabolic basis of heredity

Viktor Stolc - NASA Ames Research Center Moffett Field, California, USA.

Abstract [PDF]

87. Lecture [19/9/2012]

Hra zákonitostí a interpretácie v ontogenéze

Anton Markoš - Přírodovědecká fakulta Univerzity Karlovy, Praha, Česká republika.

Abstract [PDF]

86. Lecture [8/6/2012]

Plastid evolution: Lessons from the completed genome of the glaucophyte alga Cyanophora paradoxa

Wolfgang Löffelhardt - Department of Biochemistry and Cell Biology, Max F. Perutz Laboratories, University of Vienna, Austria.

Abstract [PDF]

85. Lecture [9/3/2012]

A key step in land plant evolution and function: Genetic control of the development of 3D body plan in higher plants

Odd-Arne Olsen - Norwegian University of Life Sciences, Ås & Hedmark University College, Hamar, Norway.

Abstract [PDF]

84. Lecture [24/2/2012]

Molecular phylogeny and evolution of autotrophic euglenoids - one of the most ancient  lines of eukaryotes

Anna Karnkowska-Ishikawa - Department of Plants Systematics and Geography, University of Warsaw, Poland.

Abstract [PDF]


83. Lecture [25/11/2011]

Autocrine VEGF-VEGFR2/Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

Petra Hamerlik Institute of Cancer Biology and Centre for Genotoxic Stress Research, Danish Cancer Society, Copenhagen, Denmark.

Abstract [PDF]

82. Lecture [21/10/2011]

Srovnávací genomika a evoluce protistů: Revoluce v představách o evoluci eukaryot

Marek Eliáš Department of Biology and Ecology, Faculty of Natural Sciences, University of Ostrava, Czech republic.

Abstract [PDF]

81. Lecture [14/10/2011]

RNA quality control: the tales of two 3’-end tails

Štepánka Vanačová - National Centre for Biomolecular Research, Central European Institute of Technology, Faculty of Science, Masaryk University, Brno, Czech republic. 

Abstract [PDF]

80. Lecture [20/5/2011]

RNA editing and mitochondrial translation in trypanosomes

Dmitri Maslov - University of California, Riverside,USA

Abstract [PDF]

79. Lecture [28/4/2011]

eIF3 rocks: From initiation to termination and back to reinitiation

Leoš Shivaya Valášek - Institute of Microbiology, Academy of Sciences of the Czech republic, Prague, Czech republic. 

Abstract [PDF]

78. Lecture [9/3/2011]

Bayesian inference of ancient human demography from individual genome sequences

Adam Siepel, Cornell University, USA

Abstact [PDF]

77. Lecture [21/1/2011]

Cell division and metabolism of fission yeast Schizosaccharomyces pombe

Mitsuhiro Yanagida, Okinawa Institute of Science and Technology Promotion, Kyoto University, Kyoto, Japan

Abstract [PDF]


76. Lecture [1/12/2010]

Architektúra buněčného jádra a nemoc

Ivan Raška, Ústav buněčné biologie a patologie, Univerzita Karlova, Praha

Abstract [PDF]

75. Lecture [19/11/2010]

Schistosoma japonicum genome project – the gap between genomics and biology

Yan Zhou, Fudan University and Chinese National Human Genome Center, Shanghai, China

Abstract [PDF]

74. Lecture [18/05/2010]

Skákající geny - parazité nebo pomocníci?

Eduard Kejnovský, Laboratoř vývojové genetiky rostlin, Biofyzikální ústav AVČR Brno, ČR

Abstract [PDF] [Lecture]

73. Lecture [11/03/2010]

Vznik eukaryotické buňky

Vladimír Hampl, Katedra parazitológie a hydrobiológie, Prírodovedecká fakulta Univerzity Karlovy, Praha, ČR

Abstract [PDF]


72. Lecture [27/11/2009]

Detecting natural selection with empirical codon models

Carolin Kosiol, Institute of Population Genetics, University of Veterinary Medicine, Vienna, Austria

Abstract [PDF]

71. Lecture [25/11/2009]

Genome wide analysis of environmental stress response in yeast and close relatives

Christoph Schüller, University of Vienna / Max F.Perutz Laboratories, Vienna, Austria

Abstract [PDF]

70. Lecture [15/4/2009]

Reverse origami: Discovery of new genomic ribozymes and aptamers

Andrej Lupták, University of California Irvine, USA

Abstract [PDF]


69. Lecture [9/12/2008]

Hedvábí, kutikula a juvenilní hormon

František Sehnal, Biologické centrum, Entomologický ústav AV ČR, České Budějovice, Česká republika.

Abstract [PDF]

68. Lecture [17/4/2008]

Mitochondrial electron redox chain as a new target for anti-cancer drugs

Jiří Neužil, Apoptosis Research Group, School of Medical Science, Griffith University, Southport, Qld, Australia & Molecular Therapy Group, Institute of Biotechnology, Academy of Sciences of the Czech republic, Prague, Czech republic. 

Abstract [PDF]

67. Lecture [30/1/2008]

Od ADP/ATP translokátora k bunkovej smrti

Peter Polčic, Department of Biochemistry, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia.

Abstract [PDF]

66. Lecture [15/1/2008]

Ako sa mozog učí: úloha génov

Ľubica Beňušková, Department of Computer Science, University of Otago, Dunedin, New Zealand & Department of Applied Informatics, Faculty of Mathematics, Physics and Informatics, Comenius University, Bratislava, Slovakia.

Abstract [PDF]


65. Lecture [20/11/2007]

Molekulární a fenotypové hodnocení diverzity cyanobakterií: Moderní kombinované aspekty klasifikace

Jiří Komárek, Jihočeská univerzita, České Budějovice, Česká republika.

Abstract [PDF]

64. Lecture [31/10/2007]

Sex and reproduction: ready for divorce?

Carl Djerassi, Department of Chemistry, Stanford University, USA.

Abstract [PDF]

63. Lecture [19/4/2007]

Lipid biogenesis in yeasts

Günther Daum, Institute of Biochemistry, University of Technology, Graz, Austria. 

Abstract [PDF]

62. Lecture [30/3/2007]

Two novel pathways of signal transduction in Bacillus subtilis cannibalism system

Richard M. Losick, Department of Molecular and Cell Biology Harvard University, Cambridge, USA.

Abstract [PDF]

61. Lecture [16/3/2007]

Ups and downs of homologous recombination

Lumír Krejčí, National Centre for Biomolecular Research, Masaryk University, Brno, Czech Republic.

Abstract [PDF]

60. Lecture [9/3/2007]

Chromatin structures dynamics - functions of SMC proteins

Jan Paleček, Department of Functional Genomics and Proteomics Masaryk University, Brno, Czech Republic.

Abstract [PDF]

59. Lecture [22/2/2007]

Methods of molecular modeling in drug design

Igor Tvaroška, Institute of Chemistry, Slovak Academy of Sciences, Bratislava, Slovakia.

Abstract [PDF]


58. Lecture [24/10/2006]

Visualizing the ends of chromosomes and the proteins that reside there

Jack D. Griffith, University of North Carolina, Chapel Hill, USA.

Abstract [PDF]

57. Lecture [6/10/2006]

Plant Neurobiology

František Baluška, Institute of Cellular & Molecular Botany University of Bonn, Germany.

Abstract [PDF]

56. Lecture [5/5/2006]

Chromosome segregation in meiosis

Juraj Gregáň, Department of Chromosome Biology, University of Vienna, Max F. Perutz Laboratories, Vienna, Austria.

Abstract [PDF]

55. Lecture [21/4/2006]

Nucleo-mitochondrial interactions: central player in yeast retrograde signaling

Mário Špírek, Department of Chromosome Biology, Faculty of Life Sciences, University of Vienna, Austria.

Abstract [PDF]

54. Lecture [7/4/2006]

Initiation of DNA replication in Archaea, the third domain of life: How eukaryotic-like machinery functions in these prokaryotic organisms

Alan Majerník, Institute of Animal Biochemistry and Genetics Slovak Academy of Sciences, Bratislava, Slovakia.

Abstract [PDF]

53. Lecture [17/3/2006]

Time within us: Biological rhythms - mechanisms of their generation and consequences on physiological functions

Michal Zeman, Department of Animal Physiology and Ethology, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia.

Abstract [PDF]


52. Lecture [11/11/2005] 

Who is the father? (Mating strategies and reproductive success in broiler breeders)

Boris Bilčík, Institute of Animal Biochemistry and Genetics Slovak Academy of Sciences, Bratislava, Slovakia.

Abstract [PDF]

51. Lecture [7/10/2005]

The role of nucleoid-associated proteins in the organization and compaction of bacterial chromatin

Remus Thei Dame, Physics of Complex Systems, Department of Physics and Astronomy, Faculty of Sciences, Vrije Universiteit, Amsterdam, The Netherlands.

Abstract [PDF]

50. Lecture [17/5/2005]

The steroid deficiency gene ecdysoneless

Marek Jindra, Institute of Entomology, Academy of Sciences of the Czech republic, České Budějovice, Czech Republic.

Abstract [PDF]

49. Lecture [22/4/2005]

Cellular and mouse models of deregulated signaling pathways in hematopoiesis

Vladimír Divoký, Department of Biology and Hemato-Oncology, Faculty of Medicine, Palacky University, Olomouc, Czech Republic.

Abstract [PDF]

48. Lecture [7/4/2005]

Development of high throughput technologies for selections of antibodies from phage display libraries

Peter Pavlík, Bioscience Division of Los Alamos National Laboratory, Los Alamos, New Mexico, USA.

Abstract [PDF]

47. Lecture [31/3/2005]

Epigenetic inheritance and the role of sex

Boris Vyskot, Laboratory of Plant Developmental Genetics Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech republic.

Abstract [PDF]

46. Lecture [4/3/2005]

Recognition of DNA damage by bacterial nucleotide excision repair

Milan Škorvaga, Institute of Experimental Oncology Slovak Academy of Science, Bratislava, Slovakia.

Abstract [PDF]


45. Lecture [12/11/2004]

Meiosis & Telomeres: Unexpected connections

Karel Říha, Gregor Mendel Institute of Molecular Plant Biology Austrian Academy of Sciences Wienna, Austria.

Abstract [PDF]

44. Lecture [19/10/2004]

Surprising genetic heterogeneity of X-chromosome linked mental retardation

Jozef Gecz, Department of Cytogenetics and Molecular Genetics, Women´s and Children´s Hospital North Adelaide, Australia.

Abstract [PDF]

43. Lecture [04/05/2004]

Searching for Christmas trees in nucleolus

Ivan Raška, Charles University and Experimental Medicine Institute, Academy of Sciences of the Czech republic, Prague, Czech republic.

Abstract [PDF]

42. Lecture [23/04/2004]

Secret life of qubits

Vladimír Bužek, Research Center for Quantum Information, Slovak Academy of Sciences, Bratislava, Slovakia.

Abstract [PDF]

41. Lecture [18/03/2004]

Multi drug resistance in yeast

André Goffeau, Université Catholique de Louvain, Louvain-la-Neuve, Belgium.

Abstract [PDF]


40. Lecture [27/11/2003]

Calcium signaling during excitation - contraction coupling in cardiac myocytes

Alexandra Zahradníková, Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences, Bratislava, Slovakia.

Abstract [PDF]

39. Lecture [30/10/2003]

New insights into the Lon protease and DnaJ-like chaperone of human mitochondria: Roles in mtDNA metabolism and cell signaling

Carolyn Suzuki, Department of Biochemistry and Mol. Biology, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, USA.

Abstract [PDF]

38. Lecture [25/09/2003]

The role of cardiolipin in mitochondrial function: Implications for Barth syndrome

Miriam L. Greenberg, Department of Biological Sciences, Wayne State University, Detroit, Michigan, USA.

Abstract [PDF]

37. Lecture [24/06/2003]

Functional analysis of proteins involved in RNA editing in Trypanosoma brucei using RNA interference

Julius Lukeš, Institute of Parasitology, Academy of Sciences of the Czech republic, České Budějovice, Czech republic.

Abstract [PDF]

36. Lecture [22/04/2003]

Adenylate cyclase toxin of Bordetella: A model protein penetrating cellular membranes and a novel antigen delivery tool for induction of cellular immunity against viruses and tumors

Peter Šebo, Institute of Microbiology, Academy of Sciences of the Czech republic, Prague, Czech republic.

Abstract [PDF]

35. Lecture [13/02/2003]

Excretion of organic acids by filamentous fungi

Wolfgang Burgstaller, Institute of Microbiology, Faculty of Natural Sciences, University of Innsbruck, Austria.

Abstract [PDF]


34. Lecture [6/11/2002]

Plasticity of prokaryotic genome

Jiří Doškař, Masaryk University, Brno, Czech republic.

Abstract [PDF]

33. Lecture [17/10/2002]

Perspectives for the functional analysis of Chlamydomonas DIP13, a new potential microtubule associated protein

Wolfgang Mages, Universität Regensburg, Germany.

Abstract [PDF]

32. Lecture [28/05/2002]

Apoptosis in yeast

Frank Madeo, Institute for Physiological Chemistry, University of Tübingen, Germany.

Abstract [PDF]

31. Lecture [22/04/2002]

Evolutionary algorithms and modeling of cooperation

Jiří Pospíchal, Department of Mathematics, Slovak Technical University, Bratislava, Slovakia.

Abstract [PDF]


30. Lecture [14/12/2001]

Yeast as a model to characterize the role of acyl chains in membrane biogenesis

Roger Schneiter, Institute of Biochemistry, Technical University Graz, Austria.

Abstract [PDF]

29. Lecture [13/12/2001]

Genomika: minulost, současnost a budoucnost

Václav Pačes, Institute of Molecular Genetics, Academy of Sciences of the Czech republic, Prague, Czech republic.

Abstract [PDF]

28. Lecture [15/11/2001]

Yeast mother cell-specific aging

Michael Breitenbach, University of Salzburg, Austria.

27. Lecture [08/11/2001]

Exploring the catalytic core of mitochondrial complex I by yeast genetics

Ulrich Brandt, Gustav-Embden Zentrum der Biologischen Chemie, Frankfurt am Main, Germany.

26. Lecture [08/11/2001]

Polycythemias, cancer, erythropoietin, von Hippell-Lindau gene and hypoxia signalling

Josef T. Prchal, Baylor College of Medicine, Houston, TX, USA.

25. Lecture [28/05/2001]

X-linked bone disease - SEDL, interplay of gene and its pseudogene

Jozef Gecz, Women's and Children's Hospital, Adelaide, Australia.

24. Lecture [12/03/2001]

The importance of mitochondrial uncoupling proteins for lipid metabolism

Jan Kopecký, Institute of Physiology, Academy of Sciences of the Czech republic, Prague, Czech republic.

23. Lecture [27/02/2001]

Proteosynthesis in kinetoplasts

Anton Horváth, Department of Biochemistry, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia.

22. Lecture [29/11/2000]

Slovenskí vysokoškolskí učitelia: Akí boli, sú a budú?

Soňa Szomolányi & Ladislav Kováč, Comenius University, Bratislava, Slovakia.


21. Lecture [27/10/2000]

What yeast glycolysis may lead to and beyond

H. Yde Steensma, Leiden University, The Netherlands.

20. Lecture [17/10/2000]

Using the genome project to understand the development of plant cells

Liam Dolan, John Innes Center, Norwich, UK.

19. Lecture [25/09/2000]

Osmotic stress signalling: A trip from membrane to chromosome

Vladimír Reiser, Harvard Medical School, Boston, MA, USA.

18. Lecture [22/05/2000]

Mitochondrial genetics and metabolism of pyrimidines in Saccharomyces yeasts.

Jure Piškur, Technical University of Denmark, Lyngby, Denmark.


17. Lecture [28/06/1999]

Antibody-independent killing of group B Streptococcus

Peter Butko, University of Southern Mississippi, Hattiesburg, MS, USA.

16. Lecture [18/06/1999]

Are mitochondrial channels the gatekeepers of cell death?

Kathleen W. Kinnaly, Wadsworth Center, Albany, NY, USA.

15. Lecture [18/06/1999]

Regulation of the yeast transcriptional activator Gal4

Karin D. Breunig, Martin-Luther-University Halle, Germany.

14. Lecture [19/05/1999]

Darwin: Philosopher of the 21th century

Werner Callebuat, University of Maastricht, The Netherlands.

13. Lecture [16/04/1999]

Life under anoxic conditions: Transmembrane ion current and the mechanism of ATP synthesis in methanogenic and acetogenic microorganisms

Volker Müller, Ludwig-Maximilian University, Munich, Germany.

12. Lecture [08/04/1999]

Distribution of actin and tubulin during the cell division of Endomyces magnusii

Jiří Hašek, Institute of Microbiology, Academy of Sciences of the Czech republic, Prague, Czech republic.


11. Lecture [23/11/1998]

Telomeres and subtelomeres of plant chromosomes

Jiří Fajkus, Masaryk University, Brno, Czech republic.

10. Lecture [28/09/1998]

To be or not to be? The role of IAP genes in apoptosis

Martin Holčík, University of Ottawa, Canada.

9. Lecture [30/03/1998]

The role of ABC transporters in the immune response

Gustav Russ, Institute of Virology, Slovak Academy of Sciences, Bratislava, Slovakia.


8. Lecture [05/12/1997]

Darkener of apricot (Doa) - a new gene, a new evolutionary conserved protein kinase

Róbert Farkaš, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia.

7. Lecture [24/10/1997]

Biological roots of morality

Franz M. Wuketits, University of Vienna, Austria.

6. Lecture [02/06/1997]

Molecular genetics of mental retardation

Jozef Gecz, Women's and Children's Hospital, Adelaide, Australia.

5. Lecture [09/05/1997]

The yeast genome and the genes involved in the multidrug resistance phenomenon

Claude Jacq, Ecole Normale Superieure, Paris, France.

4. Lecture [14/04/1997]

Neuroendokrínna regulácia zvliekania hmyzu alebo brušný tanec motýľov

Dušan Žitňan, Institute of Zoology, Slovak Academy of Sciences, Bratislava, Slovakia.

3. Lecture [10/03/1997]

Function of yeast ABC transporters: From sex to pleiotropic drug resistance

Karl Kuchler, University and Biocenter Vienna, Austria.


2. Lecture [28/11/1996]

Regulation and defects in biosynthesis of mitochondrial ATPase

Josef Houštěk, Institute of Physiology, Academy of Sciences of the Czech republic, Prague, Czech republic.

1. Lecture [27/09/1996]

A common denominator among CDC1, mitochondrial processing protease, sensitivity to mycobacteria and brain function

Nathan Nelson, University of Tel Aviv, Israel.

V rokoch 2010 a 2011 Kuželove semináre podporila Nadácia Tatra banky. Ďakujeme.

In 2010 and 2011 Kužela lectures have been supported by Tatra banka Foundation. Thank you very much.